The popularity of USB flash drives does not solely come from its convenient size and the amount of data it can store but also in its easy use. It is very simple to operate and use a USB flash drive provided that the computer you connect it to has all the installed drivers that support the device. However, if the computer does not have an existing driver, USB flash drive installer software is also very easy to install and operate.

The protruded "connector" of the USB flash drives is simply plug directly into the computer or to a plug which is directed to the USB port. The computer then detects the device and upon detection, a folder containing all the files in your USB flash drive would appear on the computer screen. Files can then be easily accessed and transferred to the USB flash drive simply by dragging these files or by copying them into the USB flash drive folder. After using the device, the user can simply detach the flash drive from the port and use it again similarly with other computers.

USB flash drives can be used with most computers as long as they have a USB port and the software compatible with the drive to make it run. A lot of the newer operating systems have pre-installed USB drive drivers, but for those with operating systems that are quite dated, USB flash drive makers also offer drivers which may be used with these systems. These are easy to install and to use, as well. The compatibility of the USB flash drives and the availability of drivers in order for it to run must be checked with the manufacturer before even purchasing your flash drive. However, almost all USB flash drives work well with most computers.

Using USB flash drives are even simpler and more accessible than CD-R or DVD-R, besides USB ports are more common than CD or DVD equipped computers. Also, files stored in the USB flash drives may be erased as often as the user wants it to and may be changed as well.

The novelty of USB flash drives have long gone, yet despite this, users still enjoy its power and portability.